People love this stuff, so in case you missed this…

I have something that will electrify you… It’s even better than coffee.

When I was hiking through the Amazon Rain Forest last year, I had a first-hand experience with a remarkable healing herb.

This rain forest herb gives you lasting energy – without the crash.

Sacred to the nearby Guarani tribe, it was literally a gift  the gods. According to tribal folklore, the Indians of the Amazon River Basin have been using it to prevent fatigue and increase physical endurance since before recorded history.

I took it in the early morning before we hit the trail. After 18 hours through the jungles of Peru my mind was crystal clear and I had no feeling of fatigue. Looking back, I had covered 15 miles of rugged terrain without feeling tired or worn out.

I realized that combining this ancient herb with cutting edge brain nutrients would create a powerful new formula. Not only would it give you more energy without crashing, it would help your memory too.

But the story gets better… After I got home, I started putting the pieces together. Working nights and weekends I had a trial formula within the first six weeks. Using myself as a test subject, I gave it a try.

Right  the start I knew I was on to something. I tapped into a deep source of mental energy, heightened memory and a laser-like focus throughout the day.

All the individual components of my formula are backed up by modern clinical studies. And now for the first time, you can feel the startling results for yourself.

Here’s how it works.

Better Than Coffee: Kick Start Your Morning Without Feeling Nervous or Jittery

The Amazon herb that kept me alert yet relaxed comes  a seed called Paullina cupana. The active compound is guaranine, a member of the caffeine family. But unlike regular caffeine, it’s full of healthy fatty acids.

The good fat gives guaranine a slow release. Its effect will gradually increase over a period of hours. It doesn’t pick you up and throw you down like quick release caffeine. There’s no crash with this stuff… and you don’t get any of the nervous, jittery energy you do with caffeine.

Caffeine gets a bad rap sometimes but it’s the most widely used drug in the world. And it’s a proven mental performance booster. The studies number in the hundreds. One published in Neurology found that three cups of coffee a day cuts your risk of mental decline by over 50%.₁

But there’s a catch. Coffee gives you a short burst of energy, but overheats and excites your body. Guaranine has a cooling action that revitalizes and relaxes. The end result is more beneficial to your body. You get all the energy and alertness but remain calm, cool and collected.

A team of Brazilian scientists studied the effects on rats. Their results were not surprising. Guaranine increased their physical activity, increased their physical endurance under stress and improved their memory.₂

But like I said, the story gets even better…

Better Than Coffee: Give Your Brain the Power of Total Recall and Extreme Alertness

The effect of the Paullina cupana seed was amazing. It gave the endurance to trek through the Amazon and left me with a wonderful feeling of clarity. But I was starting to see the bigger picture.

The Rain Forest herb works its magic by releasing acetylcholine in your brain. Acetyl-choline is a neurotransmitter. It’s the brain chemical that lets your nerve cells fire through the synapse or gap that exists between the trillions of neurons in your brain.

If you have lots of acetylcholine, your mind is sharp and your memory is clear. When you drink coffee in the morning, the release of acetylcholine gives you the buzz that gets you going.

But there’s a problem… coffee will burn you out because it depletes your reserve of acetylcholine. Guaranine is slow acting with none of the caffeine side effects but it works in the same way. Eventually you lose your reserve of acetylcholine.

But if you trigger a release of acetylcholine and then rebuild your reserves you can sustain the amazing rush of clarity over the long term.

That’s the Realization I Had While Hiking Through the Forest…

I knew I could get the best of both worlds if I combined guaranine with powerful brain nutrients. One of them is choline, the building block required for the synthesis of acetylcholine. Introduce choline into the mix and you give your body the ability to manufacture this incredibly powerful neurotransmitter.

When you combine choline and guaranine you get a bigger release of acetylcholine – even more than taking guaranine on its own. That’s what gives you the feeling of energy and mental power. But instead of depleting your reserves and burning out, you build them up.

That means you can take my formula every day and get the same effect every time.

Getting More Choline Is Essential –Your Brain Needs It for Thinking and Remembering

Your brain has a huge appetite for choline. It’s the primary building block for acetylcholine. You burn it up 24/7 as your brain uses it to maintain clear communication between trillions of neurons.

You need it for all the basics like thought, memory and sleep. It even controls how you move. Your muscles receive commands  your brain via acetylcholine. That means your sense of balance and stability is controlled by this key transmitter.

Like many nutrients, your supply of choline drops as you get older. As this happens, you can expect some or all of these symptoms:

• Poor recall and memory loss
• Fatigue or lack of energy
• Brain fog and/or a sense of confusion
• Problems falling asleep, tossing and turning
• Unable to catch on, or learn new things
• Feeling distracted or irritable
• Walking with a wobbly or shaky gait, unable to stay balanced

Better Than Coffee: When Your Brain Doesn’t Get Enough Choline

It Starts to Destroy Itself…

To survive, your body will scavenge materials  other sources when it can’t get enough  its main supplier. When choline levels drop off, your brain goes on a scavenger hunt and extracts choline  nerve cell membranes. This last resort is called “auto-cannibalism” and it’s very dangerous.

In the short term, your brain will use this technique to keep your memory and other functions up and running. But in the long run, your nerve cells end up badly damaged. It’s not surprising that Alzheimer’s patients have very low levels of acetylcholine. As the disease progresses, it’s the choline neurons that show the most damage.

In the graph below, you can see how the nutrients DMAE and choline turn into the key neurotransmitter acetylcholine. DMAE is another powerful brain nutrient I will tell you about a little later. It’s also in my formula. First, I want you to see the direct connection choline has to its end product acetylcholine.

As you can see, choline is one small step away  acetylcholine. Put more choline into your body and your brain gets more of the neurotransmitter that keeps your mind alert and your memory fresh.

Clinical Studies Prove Connection Between Choline and Memory

It’s very possible you’ve never heard of choline. Most people haven’t. But it’s one of the most important nutrients on the planet. And it’s well researched. There are dozens of studies testing both animals and humans.

Here are just a few:

• Researchers who gave rats a choline supplement found they developed a sharper and longer memory than rats that didn’t have extra choline. On day one, both groups of rats were performing their tasks successfully. This included avoiding electric shock as they moved through a maze.

On day two, the rats that didn’t have the extra choline forgot about the electric shock and got zapped. But the rats that had the extra choline remembered the booby traps and successfully avoided getting shocked.₃

• In a human study, researchers at Northwestern University in Chicago tested people with a choline deficiency. They gave them a series of memory tests and found below average scores. In the next stage, they divided the same people into two groups. One group received extra choline, the other didn’t.

After 24 weeks, both groups repeated the memory tests. Not surprisingly, the group with the extra choline performed with flying colors and their results showed a dramatic improvement over the first round. The group that received no extra choline performed poorly. Their results showed no improvement over the first round.4

Better Than Coffee: Burn Through Your Crossword with Lightning Speed…

My unique blend of choline and guaranine is like rocket fuel for your brain. Not only does it give you a better boost than your morning cup of coffee, it gives you the clarity of a mental giant.

You’ll notice the lift right away. If you do crosswords you’ll finish them in a fraction of the time. Things like organization, recall and comprehension just fall into place.

When you read something, you “get it.” When someone is explaining something, you understand what they’re getting at before they even get to the point. You move into a feeling of extreme alertness. You’re aware of everything and it’s all so clear.

The processing speed of your brain gets a twin-turbo boost. It’s like stepping up to one of those super-computers NASA uses for space flight.

One of the experiences I appreciate most is the “alert but calm” feeling. Your mind can relax and let go. Your focus becomes almost laser like. And it lasts throughout the day. It’s not a short-lived spike like coffee or other caffeine drinks.

I could have stopped there… choline and guaranine are enough to repair and rejuvenate your aging brain. But there’s another key brain booster essential to my formula.

Better Than Coffee: This Nutrient Works So Well It Even Caught the Attention of the Bumbling Bureaucrats at the FDA…

A little earlier I mentioned DMAE. It’s a natural, brain-stimulating nutrient found in anchovies, sardines and other fish. Studies show it increases levels of acetylcholine. As you know, acetylcholine is critical for learning and memory.₅

I’ve been following the story of DMAE for decades. It works so well the FDA finally took notice and planned to approve it to treat learning problems, behavioral problems and impaired motor conditions associated with a variety of diseases – even aging.

So what happened? The FDA discontinued it in the late 1970s after the manufacturer didn’t agree to the expensive retesting required. Since the manufacturer wouldn’t pay, the FDA dropped DMAE like a hot potato in exchange for Ritalin® and Alzheimer’s drugs.

What a shame. Unlike prescription drugs, DMAE provides a safe and non-addictive solution to a variety of cognitive and behavioral problems.

I already pointed out the connection between the mental decline of Alzheimer’s and the loss of acetylcholine. In part the disease is due to the loss of brain cells that produce acetylcholine. DMAE replaces this chemical naturally and can ease symptoms.₆

DMAE can also temper mood and ease behavioral and learning problems. In one study, 50 hyperactive kids showed improvement in just 10 weeks.₇ In another study, children with learning disabilities did better in concentration and skill tests with this nutrient.₈ And there were no side effects like jumpiness, or an increase in heart rate and blood pressure like with drugs.₉

It’s easy to see why I added DMAE to my formula. It’s one of the best memory boosters available. In combination with choline and guaranine, it’s unbeatable. It has a synergistic quality that makes the three ingredients more than the sum of their parts.

Clinical studies show DMAE can:₁₀

• Boost IQ
• Accelerate mental speed and your ability to process thoughts and ideas
• Improve your concentration and eliminate early morning “fogginess”
• Relieve the symptoms of mild depression
• Decrease irritability and over activity
• Increase attention without causing drowsiness

Eliminate Your Biggest Risk Factors for Heart Attack and Stroke

There’s one more thing you need to know about this formula… It has a very unique and clinically proven “side effect”: Your risk of heart attack and stroke plummets.

How is this possible?

Boosting the level of choline in your blood has a powerful effect on homocysteine and C-reactive protein (CRP). If you’re a regular reader you’ve probably heard about these powerful markers. They are both better predictors of heart attack and stroke than anything else – including cholesterol.

Homocysteine is not only a predictor, but also an initiator of cardiac events. It irritates the lining of blood vessels. Excess homocysteine inhibits blood vessels  dilating. This decreases blood flow at critical times of stress. Inadequate blood flow to the heart causes heart attacks. Inadequate blood flow to the brain causes strokes.

Your body produces C-reactive protein as part of its overall defense. When part of your body is injured, it sends signals to the rest of your body for help. Your immune system then sends out white blood cells and inflammatory molecules including CRP to the injured area.

Once there, the defense cells try to fix damaged areas and fight off the intruder. But this defensive response causes inflammation. The inflammatory response needs energy in the form of oxidative “fire” which can damage surrounding tissues. Inflammation of blood vessel cells is the major process leading to heart disease.

Spikes in CRP levels are an early sign of inflammation in your body. That’s why CRP is such a good indicator. We can detect hidden heart disease using CRP levels better than with cholesterol levels.

The New England Journal of Medicine published a massive study on CRP. Almost 28,000 people participated in the trial. Researchers tried to predict cardiac events like heart attack and stroke by looking at LDL cholesterol and CRP levels in the blood. They found that CRP predicted cardiac events better than LDL cholesterol.₁₁

Here’s the good news: The choline in my formula brings down your levels of both homocysteine and CRP. As the level of these markers drop, so does your risk of heart attack and stroke.

Here are a few of the studies that back this up:

• An experiment published in the American Journal of Clinical Nutrition followed two groups of men. One group ate a diet with no choline. The other group took a choline supplement. The men with no choline saw a steep rise in homocysteine. After just 10 days, their homocysteine went up by 35%.₁₂
• Researchers discovered that people who consume higher amounts of choline have lower levels of homocysteine and CRP. The study followed two groups of people. One group averaged less than 250-mg of choline a day. The other group averaged more than 310-mg of choline a day. The group who averaged above 310-mg saw their CRP drop by 22%.₁₃

Not only does choline ramp up your mental energy and protect your memory, it helps wipe out the two predictors of coming disaster.

Here’s Another Mental Boost: Confidence

If this is the first time you’ve heard about choline, you may be surprised to hear it does so much. But once you feel the results for yourself you’ll understand.

After taking my choline formula, many of my patients tell me they feel more confident about the future. Instead of sitting around the house worrying about what might happen, they feel like they’re back in the driver’s seat. That’s what happens when you have real options.

Knowledge is power. But I wouldn’t be surprised if sometimes you feel like you’re being kept in the dark. Many doctors make their patients feel like children or fools. Or both. They hand out prescriptions and give you an attitude if you ask questions. I’ve always believed real medicine is about empowerment. Not secrecy.

With this blend of super nutrients, you have the power to keep your mind clear and strong as you age. It keeps your brain young and well fed. And when it’s working in peak condition your risk of problems drop dramatically.

Greet the Morning with a Clear Head and a Warm Smile

Since I’ve been using my choline formula I haven’t touched a cup of coffee. I don’t need to. The feeling of “awakeness” I get is far better than anything  Starbucks.

And the effect lasts all day.

To get your own taste of clarity, go here now.

To Your Good Health,

Al Sears, MD

P.S. – As always, you’re protected by my personal unconditional guarantee. You can try out my new formula without taking any risk. When it arrives in your mailbox, take it inside and open it up. Use it. Get down to the bottom of the barrel and if it’s not for you just let me know. You’ll get back every dime. (Try doing that at your local vitamin store…)

1. Ritchie, K., et al. The neuroprotective effects of caffeine: A prospective study (the Three City Study). Neurology 69. 2007 Aug 7:536-545.
2. Espinola EB, et al. Pharmacological activity of Paullina cupana in laboratory animals. J Ethnopharmacol. 1997 Feb;55(3):223-9.
3. Gossell-Williams M, et al. Choline supplementation facilitates short-term memory consolidation into intermediate long-term memory of rats. West Indian Med J. 2006 Jan;55(1):4-8.
4. Buchman AL, et al. Verbal and visual memory improve after choline supplementation. JPEN J Parenter Enteral Nutr. 2001 Jan-Feb;25(1):30-5.
5. Dean Ward M.D. ‘Anti-Aging Nutrient Review and Update Part 4: DMAE Cognitive-Enhancing, Life Extending Nutrient’ Vitamin Research News, September 2004, Vol. 18, Number 8, p. 1-4.
6. Ferris SH, Sathananthan G, Gershon S, Clark C. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977; 25:241-4.
7. Coleman N., Dexheimer P., Dintascio A. Redman W. And Finnerty R., ‘Deanol in the treatment of hyperkinetic children’, Psychosomatics 1976, 17:68-72.
8. Geller S. J., ‘Comparison of a tranquilizer and a psychic energizer’ JAMA 1960, 174:89-92
9. Oettinger L., ‘The use of Deanol in the treatment of disorders of behavior in children. J Pediat 1958, 53:761-675.
10. Ibid.
11. Ridker P., et al. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. NEJM 2002 Nov 14; 347(20): 1557-1565
12. Choline deficiency in mice and humans is associated with increased homocysteine concentration. Am J Clin Nutr. 2005 Feb;81(2): 440-444.
13. Detopoulou P, et al. Dietary choline intakes in relation to concentrations of inflammatory markers: the ATTICA study. Am J Clin Nutr. 2008 Feb;87(2):424-30.

Your morning cup o’ joe may protect you from one of the most dreaded diseases of our time.

A new study published in the Journal of Alzheimer’s Disease says that drinking five medium-sized cups of coffee a day could lower your chances of Alzheimer’s and Parkinson’s.1

The study followed mice that were bred to develop Alzheimer’s. After two months of drinking water with 500 mg of caffeine added – the equivalent of five 8 oz. cups of coffee or two venti hot coffees from Starbucks – the mice performed much better on memory and thinking tests compared to mice that were given only water.

In fact, the memories of the caffeinated mice were on par with mice that didn’t have dementia at all.

Plus, the mice taking caffeine had a 50% reduction of beta amyloid, a protein often found in Alzheimer’s patients.2

And it’s not just Alzheimer’s. At least six separate studies indicate that people who drink coffee on a regular basis are up to 80% less likely to develop Parkinson’s. In fact, the newest Parkinson’s drugs contain a derivative of caffeine.3

I recommend getting your caffeine from an herbal source rather than from caffeine pills.

Here’s how you can take advantage of coffee’s health benefits:

• Drink it fresh. Grind your coffee at the time you wish to drink it. This maximizes the flavor and prevents against oxidation. Coffee’s healing properties are best when brewed fresh.
• Drink it black. The best benefits of coffee are delivered in its purest state. Adding dairy products and sweeteners may alter the taste, but it will also diminish the rewards.
• Don’t drink coffee close to bedtime. The brain, and your body, both require rest. Caffeine stimulation could negatively affect your sleep patterns.
• Steer clear of flavored coffee drinks. The flavors are most likely artificial (i.e., high fructose corn syrups) and are often laden with unwanted calories.

If you’re not fond of coffee, here are few natural caffeine sources to consider:

Black tea/Green tea – Black tea and green tea both contain caffeine. A cup of black tea has roughly 40 mg of caffeine. That’s about half as much caffeine as a regular cup of coffee. Green tea, a popular and healthy drink, contains approximately 20 mg per cup.

Guarana – A popular ingredient in many energy drinks, including my own Choline Punch, Guarana provides solid, energy-boosting benefits without the coffee jitters. The berry that Guarana comes from is high in healthy fatty acids, which are absorbed slower than water-soluble caffeine. This gives Guarana a slower release time than coffee. One 8 oz. glass of Choline Punch has 59 mg of caffeine.

To Your Good Health,

Al Sears, MD

1. Arendash Gary W. et al. “Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer’s Disease Mice,” Journal of Alzheimer’s Disease. July 2009
2. Chuanhai Cao et al. “Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer’s Disease Transgenic Mice,” Journal of Alzheimer’s Disease. July 2009
3. Brunilda Nazario, MD. Coffee the New Health Food? April 12, 2004 www.somalibantu.com