Telomere Studies

Welcome to the Telomere Studies research resources. Select the section and view the telomere research on the topic.


Aging

Depression Gets Old Fast: Do Stress and Depression Accelerate Cell Aging?
Owen M. Wolkowitz, M.D., Elissa S. Epel, PhD, Victor I Reus, M.D., and Synthis H. Mellon, PhD.
Department of Psychiatry, University of California School of Medicine, San Francisco, California, USA.
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Making Cells Live Forever in Quest for Cures
Wall Street Journal | By Shirley S. Wang
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Telomere-dependent senescent phenotype of lens epithelial cells as a biological marker of aging and cataractogenesis
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Telomere length, stem cells and aging
Maria A Blasco, Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre, Madrid, Spain. Published online 17 September 2007/ Nature Chemical Biology 2007.38
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Inside chromosomes are telomeres that age as we age, and may serve as indicators of how long we’ll live
L.A. Times |Cathryn Delude
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Enzyme takes us a step closer to eternal youth
NewScientist | Linda Geddes
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Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Antonia Tomás-Loba, Ignacio Flores, Pablo J. Fernández-Marcos, María L. Cayuela, Antonio Maraver, Agueda Tejera, Consuelo Borrás, Ander Matheu, Peter Klatt, Juana M. Flores, José Viña, Manuel Serrano and Maria A. Blasco
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Lifestyle change may reduce aging, disease
Read full article >>

Increased telomerase activity and comprehensive lifestyle changes: a pilot study
Prof Dean Ornish MD, Jue Lin PhD, Jennifer Daubenmier PhD, Gerdi Weidner PhD, Elissa Epel PhD, Colleen Kemp MSN, Mark Jesus M Magbanua PhD, Ruth Marlin MD, Loren Yglecias BA, Prof Peter R Carroll MD and Prof Elizabeth H Blackburn PhD
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Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
Masayuki Kimura, Jacob v. B. Hjelmborg, Jeffrey P. Gardner, Lise Bathum, Michael Brimacombe, Xiaobin Lu, Lene Christiansen, James W. Vaupel, Abraham Aviv, and Kaare Christensen; American Journal of Epidemiology Advance Access
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Alzheimer’s

Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
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Atherosclerosis

Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
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Brain

Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older
Ken-Ichi Nakamura, Kaiyo Takubo, Naotaka Izumiyama-Shimomura, Motoji Sawabe, Tomio Arai, Hiroshi Kishimoto, Mutsunori Fujiwara, Motonobu Kato, Mitsuo Oshimura, Akio Ishii, Naoshi Ishikawa. Experimental Gerontology, 2007.
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Cancer

Telomere Length and Risk of Incident Cancer and Cancer Mortality
Peter Willeit, MD; Johann Willeit, MD; Agnes Mayr, MD; Siegfried Weger, MD; Friedrich Oberhollenzer, MD; Anita Brandstätter, PhD; Florian Kronenberg, MD; Stefan Kiechl, MD
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The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
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Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Antonia Tomás-Loba, Ignacio Flores, Pablo J. Fernández-Marcos, María L. Cayuela, Antonio Maraver, Agueda Tejera, Consuelo Borrás, Ander Matheu, Peter Klatt, Juana M. Flores, José Viña, Manuel Serrano and Maria A. Blasco
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Tumor-Induced Senescent T Cells with Suppressor Function: A Potential Form of Tumor Immune Evasion
Carolina L. Montes, Andrei I. Chapoval, Jonas Nelson, Vbenosa Orhue, Xiaoyu Zhang, Dan H. Schulze, Scott E. Strome, and Brian R. Gastman
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Pharmacological intervention strategies for affecting telomerase activity: Future prospects to treat cancer and degenerative disease

I. Ta´rka´nyi, 3rd Department of Internal Medicine, University of Debrecen, 22 Moricz Zsigmond Krt., Debrecen 4004, Hungary, J. Aradi, Department of Biochemistry and Molecular Biology, University of Debrecen, 1 Egyetem te´r, Debrecen 4010, Hungary, Research Center for Molecular Medicine, Medical and Health Science Center, University of Debrecen, 1 Egyetem te´r, Debrecen 4010, Hungary
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Telomere shortening and aging
H. Jiang, Z. Ju, K.L. Rudolph; Z Gerontol Geriat 40:314-324; 2007
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Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older
Ken-Ichi Nakamura, Kaiyo Takubo, Naotaka Izumiyama-Shimomura, Motoji Sawabe, Tomio Arai, Hiroshi Kishimoto, Mutsunori Fujiwara, Motonobu Kato, Mitsuo Oshimura, Akio Ishii, Naoshi Ishikawa. Experimental Gerontology, 2007.
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Cellular senescence: when bad things happen to good cells
Judith Campis and Fabrizio d’Adda di Fagagna; Nature Reviews | Molecular Cell Biology Volume 8 | 729
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Telomeres: Cancer to Human Aging
Sheila A. Stewart – Departments of Cell Biology and Physiology and of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, and Robert A. Weinberg – Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142. Annu Rev Cell Dev Biol. 2006;22:531-57
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Cardiovascular

Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall
Christian Werner MD, Tobias Fürster MD, Thomas Widmann MD, Janine Pöss MD, Cristiana Roggia MD, Milad Hanhoun MD, Jürgen Scharhag MD, Nicole Büchner DBBSc, Tim Meyer MD, Wilfried Kindermann MD, Judith Haendeler PhD, Michael Böhm MD, and Ulrich Laufs MD
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The telomere-telomerase axis and the heart
Kajstura J, Rota M, Urbanek K, Hosoda T, Bearzi C, Anversa P, Bolli R, Leri A. Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA.
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Role of telomeres in vascular senescence
Minamino T, Komuro I.:Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Japan. Front. Biosci. 1;13:2971-9.
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Telomere dysfunction in hypertension
Jose J. Fuster, Javier Diez and Vicente Andres. Journal of Hypertension, 25:2185-2192, 2007.
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Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study
Annette L. Fitzpatrick, Richard A. Kronmal, Jeffrey P. Gardner, Bruce M. Psaty, Nancy S. Jenny, Russell P. Tracy, Jeremy Walston, Masyuki Kimura, and Abraham Aviv. American Journal of Epidemiology 2007; 165:14-21.
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Telomere length and replicative aging in human vascular tissues
Edwin Chang and Calvin B. Harley: Proc. Natl. Acad. Sci. USA Vol. 92, pp. 11190-11194, Cell Biology
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Cell aging in relation to stress arousal and cardiovascular disease risk factors
Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH. Psychoneuroendocrinology. 2006 Apr;31(3):277-87.
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Dementia

Evidence that Aging and Amyloid Promote Microglial Cell Senescence
Barry E. Flanary, Nicole W. Sammons, Cuong Nguyen, Douglas Walker, and Wolfgang J. Streit.
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Exercise

Phys Ed: How Exercising Keeps Your Cells Young
By Gretchen Reynolds, New York Times Health Blog
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Skeletal muscle telomere length in healthy, experienced, endurance runners
Dale E. Rae1, 7 , Alban Vignaud2, 3, Gillian S. Butler-Browne2, 3, Lars-Eric Thornell4, Colin Sinclair-Smith5, E. Wayne Derman1, Mike I. Lambert1 and Malcolm Collins6, 1
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Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity.
Mech Ageing Dev. 2010 Feb;131(2):165-167. Epub 2010 Jan 12. Larocca TJ, Seals DR, Pierce GL. Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
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Coupling Aging Immunity with a Sedentary Lifestyle: Has the Damage Already Been Done?
Richard J. Simpson, Keith Guy
Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston, Houston, Tex., USA
Gerontology (DOI: 10.1159/000270905)
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The biology of satellite cells and telomeres in human skeletal muscle: effects of aging and physical activity
Scand J Med Sci Sports. Kadi F, Ponsot E.
School of Health and Medical Sciences, Division of Sport Sciences, Orebro University, Orebro, Sweden.
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The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length
Lynn F. Cherkas, PhD; Janice L. Hunkin, BSc; Bernet S. Kato, PhD; J. Brent Richards, MD; Jeffrey P. Gardner, PhD; Gabriela L. Surdulescu, MSc; Masayuki Kimura, MD, PhD; Xiaobin Lu, MD; Tim D. Spector, MD, FRCP; Abraham Aviv, MD; Arch Intern Med. 2008;168(2):154-158
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FISH

Flow cytometry and FISH to measure the average length of telomeres (flow FISH)
Baerlocher GM, Vulto I, de Jong G, Lansdorp PM Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia, V5Z 1L3, Canada. . Nat Protoc. 2006;1(5):2365-76.
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Telomere Length Measurements in Leukocyte Subsets by Automated Multicolor Flow-FISH
Gabriela M. Baerlocher1 and Peter M. Lansdorp. . Cytometry Part A 55A:1-6, 2003
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Genetics

Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
Masayuki Kimura, Jacob v. B. Hjelmborg, Jeffrey P. Gardner, Lise Bathum, Michael Brimacombe, Xiaobin Lu, Lene Christiansen, James W. Vaupel, Abraham Aviv, and Kaare Christensen; American Journal of Epidemiology Advance Access
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Telomere length predicts survival independent of genetic influences
Stephanie L. Bakaysa, Lorelei A. Mucci, P. Eline Slagboom, Dorret I. Boomsma, Gerald E. McClearn, Boo Johansson and Nancy L. Pedersen. Aging Cell, 2007
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Shared environmental factors associated with telomere length maintenance in elderly male twins
Nazmul Huda, Hiromi Tanaka, Brittney-Shea Herbert, Terry Reed and David Gilley Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Aging Cell, 2007
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Telomere length is paternally inherited and is associated with parental lifespan
Njajou OT, Cawthon RM, Damcott CM, Wu SH, Ott S, Garant MJ, Blackburn EH, Mitchell BD, Shuldiner AR, Hsueh WC. Proc Natl Acad Sci U S A. ;104(29):12135-9
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HIV

Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes1
Steven Russell Fauce, Beth D. Jamieson , Allison C. Chin, Ronald T. Mitsuyasu , Stan T. Parish, Hwee L. Ng, Christina M. Ramirez Kitchen, Otto O. Yang, Calvin B. Harley , and Rita B. Effros. Department of Pathology and Laboratory Medicine and Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095; Geron, Menlo Park, CA 94025; and Department of Biostatistics, University of California-Los Angeles, School of Public Health, Los Angeles, CA 90095
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Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
Read full article >>

Telomerase induction in T cells: A cure for aging and disease?
Rita B. Effros, Experimental Gerontology, Volume 42, Issue 5, 416-420
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Telomere and adaptive immunity
Nan-ping Weng. Laboratory of Immunology, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, United States; Mechanisms of Aging and Development 2008
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Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
Read full article >>

Telomere length in human natural killer cell subsets
Ouyang Q, Baerlocher G, Vulto I, Lansdorp PM. Terry Fox Laboratory, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L3. Ann N Y Acad Sci. ;1106:240-52
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Telomerase induction in T cells: A cure for aging and disease?
Rita B. Effros, Experimental Gerontology, Volume 42, Issue 5, 416-420
Read full article >>

Telomeres: Cancer to Human Aging
Sheila A. Stewart – Departments of Cell Biology and Physiology and of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, and Robert A. Weinberg – Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142. Annu Rev Cell Dev Biol. 2006;22:531-57
Read full article >>


Immune System

Tumor-Induced Senescent T Cells with Suppressor Function: A Potential Form of Tumor Immune Evasion
Carolina L. Montes, Andrei I. Chapoval, Jonas Nelson, Vbenosa Orhue, Xiaoyu Zhang, Dan H. Schulze, Scott E. Strome, and Brian R. Gastman
Read full article >>

Telomere and adaptive immunity
Nan-ping Weng. Laboratory of Immunology, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, United States; Mechanisms of Aging and Development 2008
Read full article >>

Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
Read full article >>

Telomere length in human natural killer cell subsets
Ouyang Q, Baerlocher G, Vulto I, Lansdorp PM. Terry Fox Laboratory, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L3. Ann N Y Acad Sci. ;1106:240-52
Read full article >>

Telomerase induction in T cells: A cure for aging and disease?
Rita B. Effros, Experimental Gerontology, Volume 42, Issue 5, 416-420
Read full article >>

Telomeres: Cancer to Human Aging
Sheila A. Stewart – Departments of Cell Biology and Physiology and of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, and Robert A. Weinberg – Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142. Annu Rev Cell Dev Biol. 2006;22:531-57
Read full article >>


Lifestyle

Increased telomerase activity and comprehensive lifestyle changes: a pilot study
Prof Dean Ornish MD, Jue Lin PhD, Jennifer Daubenmier PhD, Gerdi Weidner PhD, Elissa Epel PhD, Colleen Kemp MSN, Mark Jesus M Magbanua PhD, Ruth Marlin MD, Loren Yglecias BA, Prof Peter R Carroll MD and Prof Elizabeth H Blackburn PhD
Read full article >>


Longevity

Change in the telomere length distribution with age in the Japanese population
Guan JZ, Maeda T, Sugano M, Oyama J, Higuchi Y, Makino N. Mol Cell Biochem. 2007 Oct;304(1-2):353-60
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Mainstream News

Making Cells Live Forever in Quest for Cures
WALL STREET JOURNAL | By SHIRLEY S. WANG
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Inside chromosomes are telomeres that age as we age, and may serve as indicators of how long we’ll live.
L.A. Times |Cathryn Delude
Read full article >>

Enzyme takes us a step closer to eternal youth
NewScientist | Linda Geddes
Read full article >>

Lifestyle change may reduce aging, disease
Dr. Dean Ornish of the Preventive Medicine Research Institute in Sausalito, CA
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Reverse Your Aging Process
The Oprah Winfrey Show
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Osteoporosis

Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
Read full article >>


Senescence

Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall
Christian Werner MD, Tobias Fürster MD, Thomas Widmann MD, Janine Pöss MD, Cristiana Roggia MD, Milad Hanhoun MD, Jürgen Scharhag MD, Nicole Büchner DBBSc, Tim Meyer MD, Wilfried Kindermann MD, Judith Haendeler PhD, Michael Böhm MD, and Ulrich Laufs MD
Read full article >>

A two-step model for senescence triggered by a single critically short telomere
Pauline Abdallah, Pierre Luciano, Kurt W. Runge, Michael Lisby, Vincent Géli, Eric Gilson and M. Teresa Teixeira
Read full article >>

The telomere-telomerase axis and the heart
Kajstura J, Rota M, Urbanek K, Hosoda T, Bearzi C, Anversa P, Bolli R, Leri A. Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA
Read full article >>

Role of telomeres in vascular senescence
Minamino T, Komuro I.:Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Japan. Front. Biosci. 1;13:2971-9
Read full article >>

AAMG Telomere Presentation
View the presentation >>

Cellular senescence: when bad things happen to good cells
Judith Campis and Fabrizio d’Adda di Fagagna; Nature Reviews | Molecular Cell Biology Volume 8 | 729
Read full article >>

Telomeres: Cancer to Human Aging
Sheila A. Stewart – Departments of Cell Biology and Physiology and of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, and Robert A. Weinberg – Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142. Annu Rev Cell Dev Biol. 2006;22:531-57
Read full article >>


Stem Cell

Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres
Siegl-Cachedenier I, Flores I, Klatt P, Blasco MA. J Cell Biol. ;179(2):277-90
Read full article >>

Telomere shortening and aging
H. Jiang, Z. Ju, K.L. Rudolph; Z Gerontol Geriat 40:314-324; 2007
Read full article >>

Telomere and telomerase in stem cells
E Hiyama and K Hiyama, British Journal of Cancer 96, 1020-1024
Read full article >>


Stress

Association Between Telomere Length, Specific Causes of Death, and Years of Healthy Life in Health, Aging, and Body Composition, a Population-Based Cohort Study
Njajou OT, Hsueh WC, Blackburn EH, Newman AB, Wu SH, Li R, Simonsick EM, Harris TM, Cummings SR, Cawthon RM; for the Health ABC study
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Lifestyle change may reduce aging, disease
Judith Campis and Fabrizio d’Adda di Fagagna; Nature Reviews | Molecular Cell Biology Volume 8 | 729
Read full article >>

Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer’s Disease Patients
Amanda K. Damjanovic, Yinhua Yang, Ronald Glaser, Janice K. Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David Q. Beversdorf,_and Nan-ping Weng. The Journal of Immunology, 2007, 179: 4249-4254
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Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study
Annette L. Fitzpatrick, Richard A. Kronmal, Jeffrey P. Gardner, Bruce M. Psaty, Nancy S. Jenny, Russell P. Tracy, Jeremy Walston, Masyuki Kimura, and Abraham Aviv. American Journal of Epidemiology 2007; 165:14-21
Read full article >>

Accelerated telomere shortening in response to life stress
Elissa S. Epel, Elizabeth H. Blackburn, Jue Lin, Firdaus S. Dhabhar, Nancy E. Adler, Jason D. Morrow, and Richard M. Cawthon
Read full article >>

Cell aging in relation to stress arousal and cardiovascular disease risk factors
Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH. Psychoneuroendocrinology. 2006 Apr;31(3):277-87
Read full article >>


Telomerase Activation

Geron and TA Therapeutics Announce Presentation of New Data Supporting Utility of Their Small Molecule Telomerase Activator TAT0002; TAT0002 Selected as Lead Compound for HIV/AIDS Indication
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L’OREAL-UNESCO Awards Honor UCSF Biologist for Pioneering Research in DNA Synthesis
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AAMG Telomere Presentation
View the presentation >>

Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres
Siegl-Cachedenier I, Flores I, Klatt P, Blasco MA. J Cell Biol. ;179(2):277-90
Read full article >>

Telomerase-based approaches to enhance immunity to viruses during ageing
Rita Effros Presentation Summary for SENS (Aubrey de Grey) Conference 6 Sept 2007
R.B. Effros David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095-1732, USA
Read full article >>

Geron Increases Stake in TA Therapeutics Joint Venture
Read full article >>

Telomerase induction in T cells: A cure for aging and disease?
Rita B. Effros, Experimental Gerontology, Volume 42, Issue 5, 416-420
Read full article >>

Telomere and telomerase in stem cells
E Hiyama and K Hiyama, British Journal of Cancer 96, 1020-1024
Read full article >>

Telomerase Therapeutics for Degenerative Diseases
Calvin B. Harley, PhD., Geron Corporation, 230 Constitution Drive, Menlo Park, CA, USA, 94025. Current Molecular Medicine, 2005
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Cell aging in relation to stress arousal and cardiovascular disease risk factors
Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH. Psychoneuroendocrinology. 2006 Apr;31(3):277-87
Read full article >>


Telomere Length

A two-step model for senescence triggered by a single critically short telomere
Pauline Abdallah, Pierre Luciano, Kurt W. Runge, Michael Lisby, Vincent Géli, Eric Gilson and M. Teresa Teixeira
Read full article >>


Video

AAMG Telomere Presentation
View the presentation >>


Vision

Telomere-dependent senescent phenotype of lens epithelial cells as a biological marker of aging and cataractogenesis
Received 14 October 2009; revised 26 January 2010; accepted 10 February 2010
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